Lattice Light Sheet Microscopy Is A Technique To Achieve High Resolution And Faster Sampling In Microscopy

Fluorescence microscopy is a continually developing tool for imaging biological samples, however the same challenges are faced throughout the microscopy world

by Jennifer Szczepaniak Sloane | Monday 26 August 2019

Light sheet microscopy is a technique that employs scanning a sample as a plane of laser light, a second excitation lens is placed on a perpendicular axis to the detection lens. Light sheet microscopy can therefore enable faster acquisition speeds and minimise phototoxicity and photobleaching effects.

As another benefit, light sheet microscopy improves this aspect through careful selection and tuning of the period of the lattice, filtering out unwanted frequencies, therefore offering improved axial resolution.

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Julien Clavereau
Laser Quantum UK Ltd
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Monday 26 August 2019 / file under Medical | Technology